Clinical Trial -Evaluation Checklist

CITATION:_______________________________________________ ______________________________________________________ ___________________________________________________

  • Was the assignment of patients to treatments really randomized?
    ____ yes ____ no ___ unclear

    Was similarity documented?

  • Were all clinically relevant outcomes reported?
    ____ yes ____ no ___ unclear

    Mortality and morbidity?; Deaths from all causes?; Quality of life?; Were outcomes assessments blinded?

  • Were the study patients recognizably similar to your own?
    ____ yes ____ no ___ unclear

    Eligibility criteria? Primary or tertiary?

  • Were both clinical and statistical significance considered?
    ____ yes ____ no ___ unclear

    If statistically significant was difference clinically important? If not statistically significant, was study big enough to show a clinically important difference if it should occur?

  • Is the therapeutic maneuver feasible in your practice?
    ____ yes ____ no ___ unclear

    Available? Affordable? Sensible? Were contamination and co- intervention avoided? Was it blind? Was compliance measured?

  • Were all patients who entered the study accounted for at its conclusion?
    ____ yes ____ no ___ unclear

    Were drop-outs, withdrawals, non-compilers, and those who crossed over handled appropriately?

    Conclusions:

    Provided by Alan Adams, D.C.
    Chairman of the Research Division
    Los Angeles College of Chiropractic